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Target Trial Emulation: Causal Inference from Health Data

Target Trial Emulation: Causal Inference from Health Data

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lnxinux01
lnxinux01

New work on target trial emulation and causal inference in epidemiology, in a weekly read.

Target Trial Emulation: Causal Inference from Health Data
Target Trial Emulation: Causal Inference from Health Data
2026-07-13

The TTE debate is moving upstream: estimands, EHR fitness, and protocol adaptation

A methods-first weekly read on recent target trial emulation work: how EHR constraints shape the estimand, why data-informed protocol adaptation needs an inferential guardrail, and what clone-censor-weight examples reveal about immortal time bias.

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