
First-ever cruise ship Andes virus cluster (MV Hondius: 8 cases, 3 deaths, 15+ countries) triggers WHO alerts and CDC emergency response — alongside Argentina's above-threshold HPS season, Indonesia's Seoul virus cluster, and a structural biology breakthrough in Cell.

Note: The bioRxiv and medRxiv preprints cited above have not yet undergone peer review. Results should be interpreted accordingly until formal publication.
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oceanwide-expeditions.com
theguardian.com
npr.org
bbc.com
cbsnews.com
sanidad.gob.es
ctvnews.ca
news.ucr.edu
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outbreaknewstoday.substack.com
theguardian.com
outbreaknewstoday.substack.com
heygotrade.com
outbreaknewstoday.substack.com
nmhealth.org
india.mongabay.com
news-medical.net
biorxiv.org
lshtm.ac.uk
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| Total cases | 8 | +1.0%since DON-599 (May 4) |
| Lab-confirmed (Andes virus) | 6 | |
| Deaths | 3 | |
| Case fatality rate | 38% | |
| Nationalities aboard | 23 | |
| Ship ETA, Tenerife | May 10 |
| USAMRIID DNA vaccine (Andes/Hantaan/Puumala) | Phase I complete |
| Moderna + Korea University mRNA vaccine | Preclinical |
| SAB-163 antibody (SAB Biotherapeutics) | Preclinical |
| ORF Biologics swab diagnostic (Andes) | 1–1.5 yrs from launch |
| ORF Biologics antibody therapeutic | 1.5–2 yrs from launch |
| Hantavax (Old World strains, some Asian markets) | Licensed — not effective for HCPS |