Longevity Research Brief from Top Voices

Longevity Research Brief from Top Voices

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NeoDrop Official
NeoDrop Official

Weekly tracking of Peter Attia, David Sinclair, Bryan Johnson, Rhonda Patrick on longevity research, supplements, and protocols

Longevity Research Brief from Top Voices
Longevity Research Brief from Top Voices06/01/2026, 11:23:33 AM

Longevity Digest — May 25–June 1, 2026

This week's digest covers four tracked experts across seven days. David Sinclair's ER-100 partial reprogramming trial (NCT07290244) entered active recruiting — the first such therapy in human subjects — while Sinclair publicly corrected a "Can Beat Death" headline back to "can beat diseases." Rhonda Patrick posted the week's highest-signal output: a 500,000-person Nature study revising the sleep sweet spot to 6.4–7.8 hours, a creatine-caffeine interaction threshold (≈350 mg pre-workout), a methodological defense of omega-3 supplementation against a flawed 2026 study, and prenatal vitamin D data showing better child memory at age 10 with 2,800 vs. 400 IU/day. Peter Attia released a three-element supplement evaluation framework and a meta-analysis-backed resistance training protocol (2×/week, moderate load, 3–4 sets) that captures 77% of optimized strength gains. Bryan Johnson's loudest post defended his UV umbrella with a claimed 9-year skin age reversal (unverified), and he highlighted VERVE-102 PCSK9 base editing (62% LDL reduction from a single infusion) as the next wave after GLP-1s.

Longevity Research Brief from Top Voices
Longevity Research Brief from Top Voices05/25/2026, 11:24:23 AM

Longevity Digest — May 17–25, 2026

This 8-day digest covers the week's most actionable output from all four tracked experts. David Sinclair's Life Biosciences closed a $120M Series D while its first-ever human epigenetic reprogramming trial (ER-100, Phase 1) ran in patients with glaucoma and NAION. Bryan Johnson formally expanded Blueprint to a female protocol (Kate Tolo), put social-media avoidance in official protocol copy, and shared a 500,000-person multi-omics study pinning optimal sleep at 6.4–7.8 hours. Rhonda Patrick surfaced a BJSM UK Biobank study (n=17,088) showing >150 min/week exercise correlates with only 8–9% CVD risk reduction vs. >30% at 560–610 min/week, and disclosed her daily phytosomal curcumin protocol. Peter Attia published a framework for when genetic testing changes clinical decisions and covered self-collection HPV testing as an adherence tool.

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