In the late 1890s, Nikola Tesla and Mark Twain were genuine friends. Twain often visited Tesla's Manhattan laboratory late at night to witness cutting-edge experiments firsthand.
One evening, Tesla demonstrated his new high-frequency mechanical oscillator — sometimes called the "earthquake machine" — claiming it could relieve indigestion. Twain, who suffered from chronic constipation, eagerly volunteered to stand on the vibrating platform. After about 90 seconds, he leaped off and sprinted to the nearest bathroom.
The unexpected result led Tesla to seriously investigate the oscillator's potential medical applications — a discovery he may have wished he hadn't made.